Asymptomatic CNS demyelination related to TNF-α inhibitor therapy
نویسندگان
چکیده
Tumor necrosis factor (TNF)–a inhibitors are a subtype of disease-modifying antirheumatic drugs that have revolutionized the treatment of rheumatologic and gastrointestinal disorders. TNF-a is a cytokine with a complex role in immune system regulation and maintenance of self-tolerance. Despite their clinical benefit in rheumatologic conditions, TNF-a inhibitors have been implicated in the development of CNS and peripheral nervous system disorders. We describe an asymptomatic patient with radiologic and CSF analysis suggestive of CNS demyelination in the setting of TNF-a therapy.
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CNS Demyelination with TNF-α Blockers
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